The research in our group lies at the broad interface between nanomaterials science and biotechnology. This rapidly advancing research area is commonly termed as nano-biotechnology. Our research includes the basic study of structure-property relationships of nanomaterials and application of this knowledge in development of innovative materials and functional materials systems. We are interested in nanostructured materials such as porous Silicon and their interface with soft matter e.g. hydrogels, biomolecules, and living cells. Understanding these interfaces allows us to rationally design biosensors for detection of biological and chemical toxins, new drug delivery platforms, and functional responsive materials.

News and Media

ISBE 2017
4th meeting for the Israel Society of Biotechnology Engineering
Segal Lab members presenting at ISBE 2017

Technion Team Wins Discovery Award as Part of Nesta’s £10 Million Longitude Prize
Team Prismatix developed a rapid antibiotic susceptibility test, winning an international prize as part of Nesta’s Longitude Prize competition
Read more…

Team Prismatix: Prof. Ester Segal, Heidi Leonard and Liran Holtzman from the Department of Biotechnology and Food Engineering at the Technion (upper panel, left to right). Prof. Leigh Canham from the University of Birmingham, Prof. Ofer Nativ and Prof. Sarel Halachmi from the Department of Urology at Bnai Zion Medical Center (Lower panel)

Just Published

Shtenberg G., Massad-Ivanir N., Khabibullin A., Zharov I., Segal E., Label-free optical monitoring of proteolytic reaction products using nanoporous silica colloidal assembl, Sensors and Actuators B: Chemical, 262, 796-800 (2018)

Krepker M., Prinz-Setter O., Shemesh R., Vaxman A., Alperstein D., Segal E., Antimicrobial Carvacrol-Containing Polypropylene Films: Composition, Structure and Function, Polymers, 10 (1), 79 (2018)
Open Access

Massad-Ivanir N., Bhunia K., Raz N., Segal E.*, Jelinek R., Synthesis and characterization of a nanostructured porous silicon/carbon dot-hybrid for orthogonal molecular detection, NPG Asia Materials, 10, e463 (2018) *corresponding author
Open Access

Arshavsky-Graham S., Massad-Ivanir N., Paratore F., Scheper T., Bercovici M., Segal E., On Chip Protein Pre-Concentration for Enhancing the Sensitivity of Porous Silicon Biosensors, ACS Sensors, 2 (12), 1767–1773 (2017)

Hirsch S., Barel B., Shpasser D., Segal E.*, Gazit O., Correlating chemical and physical changes of photo-oxidized low-density polyethylene to the activation energy of water releasePolymer Testing, 64, 194–199 (2017) *Corresponding author

Leonard H., Halachmi S., Ben-Dov N., Nativ O., Segal E., Antimicrobial Susceptibility of Bacterial Networks on Micropillar Architectures Using Intrinsic Phase-Shift Spectroscopy,  ACS Nano, 11, 6167-6177 (2017)