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Advanced Functional Materials



Leonard H., Halachmi S., Ben-Dov N., Nativ O., Segal E., Antimicrobial Susceptibility of Bacterial Networks on Micropillar Architectures Using Intrinsic Phase-Shift Spectroscopy, ACS Nano, published online.

Modh H., Witt M. Lavrentieva A., Urmann K., Segal E., Scheper T., Walter J.-G., Aptamer-based detection of adenosine triphosphate via qPCR, Talanta, 172, 199-205 (2017).

Krepker M., Shemesh R., Danin-Poleg Y., Kashi Y., Vaxman A., Segal E., Active Food Packaging Films with Synergistic Antimicrobial Activity, Food Control, 76, 117–126 (2017).

Urmann K., Reich P., Walter J.-G., Beckmann D., Segal E.*, Scheper T., Rapid and Label-Free Detection of Protein A by Aptamer-Tethered Porous Silicon Nanostructures, J. of Biotechnology, published online. *Corresponding author

Bussi Y., Holtzman L., Shagan A., Segal E.*, Mizrahi B., Light-Triggered Antifouling Coatings for Porous Silicon Optical Transducers, Polym. Adv. Tech., published online. *Corresponding author


Ziloni N., Rosenberg M., Holtzman L., Schori H., Shefi O., Segal E. Prolonged Controlled Delivery of Nerve Growth Factor using Porous Silicon Nanostructures, Journal of Controlled Release, published online.

Massad-Ivanir N., Shtenberg G., Raz N., Gazenbeek C., Budding D., Bos M.P, Segal E., Porous Silicon-Based Biosensors: Towards Real-Time Optical Detection of Target Bacteria in the Food Industry, Scientific Reports, 6, Article number: 38099 (2016)

K Urmann, S Arshavsky-Graham, JG Walter, T Scheper, E Segal., Whole-cell detection of live lactobacillus acidophilus on aptamer-decorated porous silicon biosensorsAnalyst 141 (18), 5432-5440

Ude C., Ben-Dov N., Jochums A., Li Z., Segal E., Scheper T., Beutel S., Online analysis of protein inclusion bodies produced in E. coli by monitoring alterations in scattered and reflected light, Applied Microbiology and Biotechnology, 100 (9), 4147-4159 (2016).

Shemesh R., Krepker M., Nitzan N., Vaxman A., Segal E.Active packaging containing encapsulated carvacrol for control of postharvest decayPostharvest Biology and Technology, 118, 175-182

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Vilenski R., Bercovici M., Segal E., Oxidized Porous Silicon Nanostructures enabling Electrokinetic Transport for Enhanced DNA DetectionAdv. Funct. Mater., 25, 6725–6732 (2015).

Featured on the cover page of Advanced Functional Materials  – Vol. 25, No. 43.

Shemesh R., Krepker M., Nathan M., Danin-Poleg Y., Banin E., Kashi Y., Nitzan N., Vaxman A., Segal E., Novel LDPE/ Halloysite Nanotubes Composites with Sustained Carvacrol Release for Broad-Spectrum Antimicrobial ActivityRSC Advances, 5, 87108–87117 (2015).

Tenenbaum E. and Segal E.Optical Biosensors for Bacteria Detection by a Peptidomimetic Antimicrobial CompoundAnalyst, 140, 7726-7733 (2015).Shtenberg G., Massad-Ivanir N., Segal E., Detection of Trace Heavy Metal Ions in Water by Nanostructured Porous Si Biosensors, Analyst, 140, 4507-4514 (2015).

Shtenberg G., Massad-Ivanir N., Segal E., Detection of Trace Heavy Metal Ions in Water by Nanostructured Porous Si Biosensors, Analyst, 140, 4507-4514 (2015).

Weitz I.S., Maoz M., Panitz D., Eichler S., Segal E., Combination of Copper Oxide Nanoparticles and Fluconazole: An Efficient Treatment against Candida AlbicansJ. Nanoparticle Res., 17(8), 342-351 (2015).

Tzur Balter A., Shatsberg Z., Beckerman Z., Segal E.*, Artzi N., Mechanism of Erosion of Nanostructured Porous Si Drug Carriers in Neoplastic TissuesNature Communications, 6, 6208 (2015). *Corresponding author.

Open access

Tzur Balter A., Shtenberg G., Segal E.Porous Silicon for Cancer Therapy: From Fundamental Research to the ClinicReviews in Chemical Engineering, 31 (3), 193-207 (2015).

Tenenbaum E., Ben Dov N., Segal E.Tethered Lipid Bilayers within Porous Si Nanostructures: A platform for Real-Time Optical Monitoring of Membrane-Associated ProcessesLangmuir, 31 (18), 5244-5251 (2015).

Urmann K., Tenenbaum E., Walter J.-G., Segal E., Porous Silicon Biosensors Employing Emerging Capture Probes, in Electrochemically Engineered Nanoporous Materials – Methods, Properties and Applications” edited by D. Losic and A. Santos, Springer-Verlag, 2015.

Shemesh R., Goldman D., Krepker M., Danin-Poleg Y., Kashi Y., Vaxman A., Segal E., LDPE/Clay/Carvacrol Nanocomposites with Prolonged Antimicrobial ActivityJ. Appl. Polym. Sci., 132(2), 41261-41269 (2015).

Shemesh R., Krepker M., Goldman D., Danin-Poleg Y., Kashi Y., Nitzan N., Vaxman A., Segal E., Antibacterial and Antifungal LDPE Films for Active PackagingPolym. Adv. Tech., 26(1), 110-116 (2015).

Urmann K., Walter J.-G.,  Scheper T., Segal E., Label-Free Optical Biosensors Bases on Aptamer-Modified Porous Si ScaffoldsAnalytical Chemistry, 87(3), 1999-2006 (2015).

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Mechrez G., Krepker M., Ashkenazi Y., Lellouche J-P., Segal E., Biocatalytic Carbon Nanotube Paper: ‘One-Pot’ Method for Fabrication of Enzyme-Immobilized Membranes for Nerve Agents BioremediationJ. Mat. Chem. B, 2 (7), 915-922 (2014).

Massad-Ivanir N., Mirsky Y., Nahor A., Eitan Edrei, Bonanno-Young L.M, Ben Dov N., Sa’ar A., Segal E., Trap and Track: Designing Self-Reporting Porous Si Photonic Crystals for Rapid Bacteria DetectionAnalyst, 139, 3885-3894 (2014).

Featured on the cover page of Analyst  – Vol. 139, No. 16.

Shtenberg G., Massad-Ivanir N., Fruk L., Segal E., Nanostructured Porous Si Optical Biosensors: Effect of Thermal Oxidation on Their Performance and PropertiesACS Appl. Mater. Interfaces, 6 (18), 16049–16055 (2014).

Mechrez G., Suckeveriene R.Y., Narkis M., Segal E., Polymer/Carbon Nanofillers Films Fabricated by Latex TechnologyPolym. Adv. Tech., 25(11), 1301-1306, (2014).

Massad-Ivanir N. and Segal E., Porous Si for Bacteria Detection, in Porous Silicon for Biomedical Applications, Edited by H. A. Santos, Woodhead Publishing Limited, 2014.

Bussi Y. and Segal E., Nanowires and Nanowires Composites for Biosensing, in Semiconducting Silicon Nanowires for Biomedical Applications, Edited by Jeffery L. Coffer, Woodhead Publishing Limited, 2014.

Krepker M. and Segal E., Porous Si-Polymer Composites, in Handbook of Porous Si, Edited by L. Canham, Springer, 2014.

Shtenberg G. and Segal E., Optical Biosensors, in Handbook of Porous Si, Edited by L. Canham, Springer, 2014.

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Tzur Balter A., Gilert A., Massad-Ivanir N., Segal E., Engineering Porous Silicon Nanostructures as Tunable Carriers for Mitoxantrone DihydrochlorideACTA Biomaterialia, 9, 6208-6217 (2013).

Tzur Balter A., Rubinski A., Segal E., Designing Porous Silicon-Based Microparticles as Carriers for Controlled Delivery of Mitoxantrone DihydrochlorideJ. Mater. Res., 28 (2), 231-239 (2013).

Shtenberg G., Massad-Ivanir N., Moscovitz O., Engin S., Sharon M., Fruk L., Segal E., Picking up the Pieces: A Generic Porous Si Biosensor for Probing the Proteolytic Products of EnzymesAnal. Chem., 85 (3) (2013).

Highlighted in Global Medical Discovery.

Tzur Balter A., Young J.M., Bonanno L.M., Segal E., Mathematical Modeling of Drug Release from Nanostructured Porous Si: Combining Carrier Erosion and Hindered Drug Diffusion for Predicting Release KineticsACTA Biomaterialia, 9 (9), 8346-8353 (2013).

Mirsky Y., Nahor A., Edrei E., Massad-Ivanir N., Bonanno L.M., Segal E., Sa’ar A., Optical Biosensing of Bacteria and Cells using Porous Silicon-based Photonic Lamellar GratingsAppl. Phys. Lett., 103 (3), 033702-033704 (2013).

Krepker M., Segal E., Dual-Functionalized Porous Si/Hydrogel Hybrid for Label-Free Biosensing of Organophosphorus CompoundsAnal. Chem., 85 (15), 7353–7360 (2013).

Ziloni N.§, Tzur Balter A.§Segal E.*, Shefi O., Bombarding Cancer: Biolistic Delivery of Porous Si Microparticles Carrying Anticancer DrugsScientific Reports (Nature Publishing Group), 3, 2499 (2013). §Equal contribution, *Corresponding author.

Open access

Massad-Ivanir N., Shtenberg G., Segal E., Biosensors for Bacteria DetectionJournal of Visualized Experiments. (81), e50805, doi:10.3791/50805 (2013).

Mechrez G., Suckeveriene R.Y., Narkis M., Segal E., Highly-Tunable Polymer/CNTs Nanostructures: A Rapid and Facile Approach for Controlled Architecture and Composition, Mat. Res. Soc. Symp. Proc., Vol. 1505 (2013).

Shtenberg G., Massad-Ivanir N., Sharon M., Fruk L., Segal E., Biosensor Based on DNA Directed Immobilization of Enzymes onto Optically Sensitive porous Si, Mat. Res. Soc. Symp. Proc., Vol. 1569 (2013).

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Massad-Ivanir N., Shtenberg G., Segal E., Advancing Nanostructured Porous Si-Based Optical Transducers for Label Free Bacterial DetectionAdv. Exp. Med. Biol., 733, 37-45 (2012).

Mechrez G., Suckeveriene R.Y., Tchoudakov R., Kigly A., Segal E.*, Narkis M., Structure and Properties of Multi-walled Carbon Nanotube Porous Sheets with Enhanced ElongationJ. Mater. Sci., 47(16), 6131-6140 (2012). *Corresponding author.

Mechrez G., Suckeveriene R.Y., Zelikman E., Rosen J., Ariel-Sternberg N., Cohen R., Narkis M., Segal E.,Highly-Tunable Polymer/Carbon Nanotubes Systems: Preserving Dispersion Architecture in Solid Composites via Rapid MicrofiltrationACS Macro Letters, 1, 848–852 (2012).

Massad-Ivanir N., Friedman T., Nahor A., Eichler S., Bonanno L.M., Sa’ar A., Segal E., Hydrogels Synthesized in Electrochemically-Machined Porous Si Hosts: Effect of Nano-Scale Confinement on Polymer PropertiesSoft Matter, 8 (35), 9166 – 9176 (2012).

Shtenberg G., Massad-Ivanir N., Engin S., Sharon M., Fruk L., Segal E., DNA-Directed Immobilization of Horseradish Peroxidase onto Porous SiO2 Optical TransducersNanoscale Research Letters, 7, 443 (2012).

Open access

Wei Y., Wan M., Wen T-C., Chang T-K., Shi G., Qi H., Tao L., Segal E., Narkis M., Nanostructured Conducting Polymers for Sensor Development, in Semiconducting Polymer Composites, Edited by X. N. Yang. Wiley-VCH, Germany 2012.

Tzur-Balter A., Massad-Ivanir N., Segal E., Surface Engineered Porous Silicon-based Nanostructures for Cancer Therapy, Mat. Res. Soc. Symp. Proc., Vol. 1416 (2012).

Segal E., Massad-Ivanir N., Shtenberg G., Krepker M., Functional Nanostructured Porous Si/Hydrogel Hybrids: Synthesis, Characterization and Applications, Mat. Res. Soc. Symp. Proc., Vol. 143, 201-206 (2012).

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Massad N., Shtenberg G., Tzur A., Krepker M., Segal E., Engineering Nanostructured Porous SiO2 Surfaces for Bacteria Detection via “Direct-Cell-Capture”Anal. Chem., 83, 3282–3289 (2011).

Bonanno L.M and Segal E., Nanostructured Porous Silicon-Polymer Based Hybrids: From Biosensing to Drug DeliveryNanomedicine, 6(10), 1755-1770 (2011).

Zeidman T., Parosh R., Massad N., Segal E., Compatibility of Cancer Cells with Nanostructured Porous SiO2Substrates, Phys. Status Solidi C, 8, 1903–1907 (2011).

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Perelman L.A., Singelyn J., Moore T., Sailor M.J., Segal E., Preparation and characterization of a multifunctional poly(N-isopropylacrylamide-co-acrylic acid)/porous SiO2 hybrid, Adv. Funct. Mater., 20, 826-833 (2010).

Massad N., Shtenberg G., Zeidman T., Segal E., Construction and Characterization of Porous SiO2/Hydrogel Hybrids as Optical Biosensors for Rapid Detection of Bacteria, Adv. Funct. Mater., 20, 2269-2277 (2010).

Featured in “Technion News”,, Walla News, Maariv News.

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Segal E.*, Perelman L.A., Moore T., Kesselman E., Sailor M.J., Grafting Stimuli-Responsive Polymer Brushes to Freshly-Etched Porous Silicon, Phys. Status Solidi C, 6(7), 1717-1720 (2009). *Corresponding author.

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Wu E., Park J., Park J.S, Segal E., Cunin F., Sailor M.J., Oxidation-Triggered Release of Small Molecules and Drugs from Mesoporous Si MicroparticlesACS Nano, 2 (11), 2401-2409 (2008). pdf

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Park J.S, Meade S.O, Segal E., Sailor M.J., Porous Silicon-based Polymer Replicas Formed by Bead PatterningPhys. Stat. Sol. (a), 204, 1383-1387 (2007).

Segal E., Perelman L.A., Cunin F., Di Renzo F., Devoisselle J.M., Li Y., Sailor M.J., Confinement of Thermoresponsive Hydrogels in Nanostructured Porous Silicon Dioxide TemplatesAdv. Funct. Mater., 17, 1153-1162 (2007).

Featured as “Advances in Advance”.

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Cooper H., Segal E., Srebnik S., Tchoudakov R., Narkis M., Siegmann A., Electrically Conductive Sensors for Liquids Based on Quaternary EVA/Copolyamide/Maleated-EVA/Polyaniline BlendsJ. Appl. Polym. Sci., 101, 110-117 (2006).

Park J., Derfus A.M., Segal E., Vecchio K.S, Bhatia S.N., Sailor M.J., Local Heating of Discrete Droplets using Magnetic Porous Silicon-based Photonic CrystalsJ. Am. Chem. Soc., 128, 7938-7946 (2006). pdf

Featured in New Scientist (issue 2555, 10 June 2006, page 32) and Research Highlights of Lab on a Chip (6, 2006, page 1115).

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Shivakumar E., Das C.K., Segal E., Narkis M., Viscoelastic Properties of Ternary in situ Elastomer Composites based on Fluorocarbon, Acrylic Elastomers and Thermotropic Liquid Crystalline Polymer BlendsPolymer, 46, 3363-3371 (2005).

Segal E., Tchoudakov R., Narkis M., Siegmann A., Wei Y., Polystyrene/Polyaniline Nanoblends for Sensing of Aliphatic AlcoholsSensors and Actuators B., 104, 140-150 (2005).

Segal E., Tchoudakov R., Mironi-Harpaz I., Narkis M., Siegmann A., Chemical Sensing Materials Based on Electrically Conductive Immiscible Polymer BlendsPolym. Int., 54, 1065-1075 (2005).

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Jia W., Tchoudakov R., Segal E., Narkis M., Siegmann A., Electrically Conductive Composites Based on Epoxy Resin Containing Polyaniline-DBSA and Polyaniline-DBSA-Coated Glass Fibers, J. Appl. Polym. Sci., 91, 1329-1334 (2004).

Cooper H., Segal E., Srebnik S., Tchoudakov R., Narkis M., Siegmann A., Electrically Conductive Sensors for Liquids Based on Ternary Immiscible Polymer Blends Containing PolyanilinePolym. Adv. Mater., 15, 573-582 (2004).

Segal E., Tchoudakov R., Narkis M., Siegmann A., Sensors for Chemicals based on Electrically Conductive Immiscible HIPS/TPU Blends Containing Carbon BlackJ. Mater. Sci., 39, 5673-5682 (2004).

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Segal E., Tchoudakov R., Narkis M., Siegmann A., Sensing of Liquids by Electrically Conductive Immiscible PP/TPU Blends Containing Carbon Black, J. Polym. Sci: Part B: Polymer Physics, 41, 1428-1440 (2003).

Jia W., Tchoudakov R., Segal E., Yoseph R., Narkis M., Siegmann A., Electrically Conductive Composites Based on Epoxy Resin with Polyaniline-DBSA Fillers, Synthetic Metals, 132, 269-278 (2003).

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Jia W., Segal E., Narkis M., Polymerization of Anilinium-DBSA in the Presence of Clay Particles: Kinetics and Formation of Core-shell StructuresPolym. Adv. Tech., 13, 16-24 (2002).

Jia W., Segal E., Kornemandel D., Lamhot Y., Narkis M. and Siegmann A., Polyaniline-DBSA/Organophilic Clay Nanocomposites: Synthesis and CharacterizationSynthetic Metals, 128, 115-120 (2002).

Segal E., Tchoudakov R., Narkis M., Siegmann A., Thermoplastic Polyurethane – Carbon Black Compounds: Structure, Electrical Conductivity and Sensing of LiquidsPolym. Eng. Sci., 42, 2430-2439 (2002).

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Segal E., Haba Y., Narkis M. and Siegmann A., Polyaniline/PVAc Blends: Variation with Time of Structure and Conductivity of Films Cast from Aqueous DispersionsJ. Appl. Polym. Sci., 79, 760-766 (2001).

Segal E., Haba Y., Narkis M. and Siegmann A., On the Structure and Electrical Conductivity of Polyaniline/PS and Polyaniline/XPS BlendsJ. Polym. Sci: Part B: Polymer Physics, 39, 611-621 (2001).

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Haba Y., Segal E., Narkis M., Titelman G. and Siegmann A., Polyaniline-DBSA/Polymer Blends Prepared via Aqueous DispersionsSynthetic Metals, 110, 189-193 (2000).

Narkis M., Haba Y., Segal E., Zilberman M., Titelman G. and Siegmann A., Structured Electrically Conductive Polyaniline/Polymer BlendsPolym. Adv. Tech., 11, 665-673 (2000).

Segal E., Narkis M., Aviel O., Polymerization of Anilinium/DBSA in the Presence of Clay Particles: Catalysis and EncapsulationPolym. Eng. Sci., 40, 1915-1920 (2000).

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Haba Y., Segal E., Narkis M., Titelman G. and Siegmann A., Polymerization of Aniline in the Presence of DBSA in an Aqueous DispersionSynthetic Metals, 106, 59-66 (1999).

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